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We find that Armenians form a distinctive cluster linking the Near East, Europe, and the Caucasus.

We show that Armenian diversity can be explained by several mixtures of Eurasian populations that occurred between ~3000 and ~2000 , a period characterized by major population migrations after the domestication of the horse, appearance of chariots, and the rise of advanced civilizations in the Near East.

The inference of population relations from haplotypes was assessed using Chromopainter (Supplementary Figure S2).

We investigated convergence by running fine STRUCTURE twice with identical parameters but different random seeds and examined the pairwise coincidence matrix visually using the fine STRUCTURE GUI.

Armenians were found to have genetic affinity to several other populations including the Jews, Druze, and Lebanese Christians, in addition to showing genetic continuity with the Caucasus.