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Let's face it: How do you drop that bomb on a potential love interest? She considered a number of online dating venues, but she says asked too many questions on its enrollment form, e Harmony was too "religious," and My Space was too much of a "hookup zone." "I wanted to meet men with my same diagnosis so we wouldn't [need to] have 'the talk,' or fear of rejection and transmitting," she says.

"Most of us with this don't wish to spread it." Despite -- or perhaps because of -- the economic downturn, the billion-dollar online dating industry has been booming. More from Health.com: Dating Tips For People With Inflammatory Bowel Disease How To Tell A New Partner A Health Secret 10 Tips For Dating With Depression While sites like and e Harmony don't discriminate, they also don't cater to people like Lana who are coping with sexually transmitted diseases, disabilities, or mental health conditions.

Love For Less Niche sites are also a lot less expensive.

Prescription 4 Love, which started charging in May 2009, is $9.95 per month, while most of the features on No Longer Lonely (including the dating service and chat rooms) are still free.

All of these can make dating -- often an ego-shattering minefield for those in perfect health -- even trickier.